Human FGF18 (His Tag) recombinant protein

Cat.#: 500546

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Product Information

  • Product Name
    Human FGF18 (His Tag) recombinant protein
  • Documents
  • Description
    Plays an important role in the regulation of cell proliferation, cell differentiation and cell migration. Required for normal ossification and bone development. Stimulates hepatic and intestinal proliferation.
  • Protein name
    Fibroblast growth factor 18
  • Protein short names
    ZFGF5; UNQ420/PRO856; FGF-18; RP23-413O19.3; D130055P09RIK; FGF18
  • Uniprot ID
    O76093
  • Gene Name
    FGF18; UNQ420/PRO856
  • Source/Expression Host
    Human Cells
  • Expression Plasmid/cDNA
    A DNA sequence encoding the human FGF18 (O76093) (Met 1-Ala 207) was fused with a polyhistidine tag at the C-terminus.
  • Protein Species
    Human
  • Molecular weight
    The secreted recombinant human FGF18 comprises 191 amino acids and has a predicted molecular mass of 22.3 kDa. The apparent molecular mass of rh FGF18 is approximately 32 kDa in SDS-PAGE under reducing conditions due to glycosylation.
  • Purity
    > 92 % as determined by SDS-PAGE
  • Activity
    1. Measured by its binding ability in a functional ELISA.
    2. Immobilized human FGF18 (Cat: 500546) at 10 μg/mL (100 μl/well) can bind  Rat FGFR4 (Cat:500770), The EC50 of Rat FGFR4 (Cat:500770) is 1.17 μg/mL.
  • Validations

    Human FGF18 / FGF-18 Protein (His Tag) SDS-PAGE

    Human FGF18 / FGF-18 Protein (His Tag) SDS-PAGE

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"