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Product Name
Human FGF18 (His Tag) recombinant protein
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Description
Plays an important role in the regulation of cell proliferation, cell differentiation and cell migration. Required for normal ossification and bone development. Stimulates hepatic and intestinal proliferation.
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Protein name
Fibroblast growth factor 18
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Protein short names
ZFGF5; UNQ420/PRO856; FGF-18; RP23-413O19.3; D130055P09RIK; FGF18
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Uniprot ID
O76093
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Gene Name
FGF18; UNQ420/PRO856
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Source/Expression Host
Human Cells
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Expression Plasmid/cDNA
A DNA sequence encoding the human FGF18 (O76093) (Met 1-Ala 207) was fused with a polyhistidine tag at the C-terminus.
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Protein Species
Human
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Molecular weight
The secreted recombinant human FGF18 comprises 191 amino acids and has a predicted molecular mass of 22.3 kDa. The apparent molecular mass of rh FGF18 is approximately 32 kDa in SDS-PAGE under reducing conditions due to glycosylation.
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Purity
> 92 % as determined by SDS-PAGE
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Activity
1. Measured by its binding ability in a functional ELISA.
2. Immobilized human FGF18 (Cat: 500546) at 10 μg/mL (100 μl/well) can bind Rat FGFR4 (Cat:500770), The EC50 of Rat FGFR4 (Cat:500770) is 1.17 μg/mL. -
Validations
Human FGF18 / FGF-18 Protein (His Tag) SDS-PAGE
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