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Product Name
FGF18 antibody
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Description
FGF18 Mouse Monoclonal antibody. Positive WB detected in HT-1080 cells, NIH/3T3 cells. Observed molecular weight by Western-blot: 21 kDa
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Tested applications
ELISA, WB
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Species reactivity
Human, Mouse; other species not tested.
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Alternative names
FGF 18 antibody; FGF18 antibody; fibroblast growth factor 18 antibody; ZFGF5 antibody
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Isotype
Mouse IgG2a
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Preparation
This antibody was obtained by immunization of FGF18 recombinant protein (Accession Number: NM_033649). Purification method: Protein A purified.
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Clonality
Monoclonal
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Formulation
PBS with 0.02% sodium azide and 50% glycerol pH 7.3.
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Storage instructions
Store at -20℃. DO NOT ALIQUOT
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Applications
Recommended Dilution:
WB: 1:500-1:5000
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Validations
HT-1080 cells were subjected to SDS PAGE followed by western blot with Catalog No:107208(FGF18 Antibody) at dilution of 1:1000
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Background
FGF18 is a member of the fibroblast growth factor (FGF) family. FGF family members possess broad mitogenic and cell survival activities, and are involved in a variety of biological processes, including embryonic development, cell growth, morphogenesis, tissue repair, tumor growth, and invasion. It has been shown in vitro that this protein is able to induce neurite outgrowth in PC12 cells. Studies of the similar proteins in mouse and chick suggested that this protein is a pleiotropic growth factor that stimulates proliferation in a number of tissues, most notably the liver and small intestine. Knockout studies of the similar gene in mice implied the role of this protein in regulating proliferation and differentiation of midline cerebellar structures.
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