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Product Name
FBP1 antibody
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Description
FBP1 Rabbit Polyclonal antibody. Positive IP detected in HepG2 cells. Positive WB detected in human liver tissue, human kidney tissue. Observed molecular weight by Western-blot: 37 kDa
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Tested applications
ELISA, WB, IP
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Species reactivity
Human,Mouse,Rat; other species not tested.
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Alternative names
FBP antibody; FBP1 antibody; FBPase 1 antibody; fructose 1 antibody; 6 bisphosphatase 1 antibody
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Isotype
Rabbit IgG
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Preparation
This antibody was obtained by immunization of FBP1 recombinant protein (Accession Number: NM_001127628). Purification method: Antigen affinity purified.
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Clonality
Polyclonal
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Formulation
PBS with 0.02% sodium azide and 50% glycerol pH 7.3.
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Storage instructions
Store at -20℃. DO NOT ALIQUOT
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Applications
Recommended Dilution:
WB: 1:500-1:5000
IP: 1:200-1:2000
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Validations
human liver tissue were subjected to SDS PAGE followed by western blot with Catalog No:110539(FBP1 antibody) at dilution of 1:500
IP Result of anti-FBP1 (IP:Catalog No:110539, 4ug; Detection:Catalog No:110539 1:500) with HepG2 cells lysate 3200ug.
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Background
FBP1(Fructose-1,6-bisphosphatase 1) is also named as FBP and belongs to the FBPase class 1 family. It catalyzes the hydrolysis of fructose-1,6 bisphosphate to fructose-6-phosphate and inorganic phosphate. This reaction is an important regulatory site of gluconeogenesis. Defects in FBP1 are the cause of fructose-1,6-bisphosphatase deficiency (FBPD)(PMID:12126934).
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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"