Anti-FBP1 Rabbit antibody

Cat.#: 167050

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Special Price 441.3 USD

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Product Information

  • Product Name
    Anti-FBP1 Rabbit antibody
  • Documents
  • Description
    FBP1 Rabbit polyclonal antibody
  • Tested applications
    WB, IHC-P
  • Species reactivity
    Human, Mouse, Rat
  • Alternative names
    FBP antibody
  • Isotype
    Rabbit IgG
  • Preparation
    Antigen: A synthetic peptide of human FBP1
  • Clonality
    Polyclonal
  • Formulation
    Supplied in 50nM Tris-Glycine(pH 7.4), 0.15M Nacl, 40%Glycerol, 0.01% sodium azide and 0.05% BSA.
  • Storage instructions
    Store at -20°C. Stable for 12 months from date of receipt.
  • Applications

    WB: 1/1000-1/5000

    IHC: 1/20-1/50

  • Validations

    Immunohistochemistry of FBP1 in paraffin-embedded Human lung cancer tissue using FBP1 Rabbit pAb at dilution 1/20

    Immunohistochemistry of FBP1 in paraffin-embedded Human lung cancer tissue using FBP1 Rabbit pAb at dilution 1/20

    Western blot detection of FBP1 in Rat Brain lysates using FBP1 Rabbit pAb(1:1000 diluted).Predicted band size:37kDa.Observed band size:37kDa.

    Western blot detection of FBP1 in Rat Brain lysates using FBP1 Rabbit pAb(1:1000 diluted).Predicted band size:37kDa.Observed band size:37kDa.

  • Background
    Swiss-Prot Acc.P09467.Catalyzes the hydrolysis of fructose 1,6-bisphosphate to fructose 6-phosphate in the presence of divalent cations, acting as a rate-limiting enzyme in gluconeogenesis. Plays a role in regulating glucose sensing and insulin secretion of pancreatic beta-cells. Appears to modulate glycerol gluconeogenesis in liver. Important regulator of appetite and adiposity; increased expression of the protein in liver after nutrient excess increases circulating satiety hormones and reduces appetite-stimulating neuropeptides and thus seems to provide a feedback mechanism to limit weight gain.

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"