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Product Name
FABP3 antibody
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Description
FABP3 Rabbit Polyclonal antibody. Positive WB detected in mouse heart tissue, HepG2 cells, human heart tissue, human skeletal muscle tissue, MCF7 cells, mouse skeletal muscle tissue, rat testis tissue. Positive IHC detected in human breast cancer tissue, human heart tissue, human lung tissue, human ovary tissue, human placenta tissue, human skin tissue, human spleen tissue, human testis tissue. Observed molecular weight by Western-blot: 15 kDa
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Tested applications
ELISA, WB, IHC
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Species reactivity
Human,Mouse,Rat; other species not tested.
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Alternative names
FABP11 antibody; FABP3 antibody; Fatty acid binding protein 3 antibody; H FABP antibody; M FABP antibody; MDGI antibody; O FABP antibody
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Isotype
Rabbit IgG
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Preparation
This antibody was obtained by immunization of FABP3 recombinant protein (Accession Number: NM_004102). Purification method: Antigen affinity purified.
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Clonality
Polyclonal
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Formulation
PBS with 0.1% sodium azide and 50% glycerol pH 7.3.
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Storage instructions
Store at -20℃. DO NOT ALIQUOT
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Applications
Recommended Dilution:
WB: 1:500-1:5000
IHC: 1:20-1:200
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Validations
mouse heart tissue were subjected to SDS PAGE followed by western blot with Catalog No:110438(FABP3 antibody) at dilution of 1:1000
Immunohistochemical of paraffin-embedded human breast cancer using Catalog No:110438(FABP3 antibody) at dilution of 1:50 (under 10x lens)
Immunohistochemical of paraffin-embedded human breast cancer using Catalog No:110438(FABP3 antibody) at dilution of 1:50 (under 40x lens)
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Background
FABP3 (fatty-acid-binding protein 3), also known as heart-type FABP or mammary-derived growth inhibitor (MDGI), is a small 15-kDa cytoplasmic protein transporting fatty acids and other lipophilic substances from the cytoplasm to the nucleus. It is most ubiquitously expressed in heart and skeletal muscle.
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References
- Shioda N, Yabuki Y, Kobayashi Y, Onozato M, Owada Y, Fukunaga K. FABP3 protein promotes α-synuclein oligomerization associated with 1-methyl-1,2,3,6-tetrahydropiridine-induced neurotoxicity. The Journal of biological chemistry. 289(27):18957-65. 2014.
- Xi L, Zhu SG, Hobbs DC, Kukreja RC. Identification of protein targets underlying dietary nitrate-induced protection against doxorubicin cardiotoxicity. Journal of cellular and molecular medicine. 15(11):2512-24. 2011.
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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"