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Product Name
Mouse ECM1 (His Tag) recombinant protein
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Description
Involved in endochondral bone formation as negative regulator of bone mineralization. Stimulates the proliferation of endothelial cells and promotes angiogenesis. Inhibits MMP9 proteolytic activity (By similarity).
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Protein name
Extracellular matrix protein 1
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Protein short names
RP11-54A4.6; URBWD; ECM1; P85; AI663821
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Uniprot ID
Q61508
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Gene Name
Ecm1
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Source/Expression Host
Human Cells
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Expression Plasmid/cDNA
A DNA sequence encoding the mouse ECM1 isoform 1 (Q61508-1) (Met 1-Glu 559) was expressed, fused with a polyhistidine tag at the C-terminus.
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Protein Species
Mouse
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Molecular weight
The secreted recombinant mouse ECM1 comprises 551 amino acids and has a predicted molecular mass of 62.5 kDa. As a result of glycosylation, the apparent molecular mass of rm ECM1 is approximately 90-95 kDa in SDS-PAGE under reducing conditions.
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Purity
> 88 % as determined by SDS-PAGE
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Activity
Measured by its ability to bind human MMP-9 in a functional ELISA.
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Validations
Mouse ECM1 Protein (His Tag) SDS-PAGE
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