ECM1 antibody

Cat.#: 107246

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Product Information

  • Product Name
    ECM1 antibody
  • Documents
  • Description
    ECM1 Mouse Monoclonal antibody. Positive WB detected in MCF7 cells. Positive IHC detected in human breast cancer. Observed molecular weight by Western-blot: 61kD
  • Tested applications
    ELISA, WB, IHC
  • Species reactivity
    human; other species not tested.
  • Alternative names
    ECM1 antibody; Secretory component p85 antibody; extracellular matrix protein 1 antibody
  • Isotype
    Mouse IgG2a
  • Preparation
    This antibody was obtained by immunization of ECM1 recombinant protein (Accession Number: NM_004425). Purification method: Protein A purified.
  • Clonality
    Monoclonal
  • Formulation
    PBS with 0.02% sodium azide and 50% glycerol pH 7.3.
  • Storage instructions
    Store at -20℃. DO NOT ALIQUOT
  • Applications

    Recommended Dilution:

    WB: 1:200-1:2000

    IHC: 1:20-1:200

  • Validations

    MCF7 cells were subjected to SDS PAGE followed by western blot with Catalog No:107246(ECM1 antibody) at dilution of 1:500

    MCF7 cells were subjected to SDS PAGE followed by western blot with Catalog No:107246(ECM1 antibody) at dilution of 1:500

    Immunohistochemical of paraffin-embedded human breast cancer using Catalog No:107246(ECM1 antibody) at dilution of 1:50 (under 10x lens)

    Immunohistochemical of paraffin-embedded human breast cancer using Catalog No:107246(ECM1 antibody) at dilution of 1:50 (under 10x lens)

    Immunohistochemical of paraffin-embedded human breast cancer using Catalog No:107246(ECM1 antibody) at dilution of 1:50 (under 40x lens)

    Immunohistochemical of paraffin-embedded human breast cancer using Catalog No:107246(ECM1 antibody) at dilution of 1:50 (under 40x lens)

  • Background
    Extracellular matrix protein 1 (ECM1) is a glycoprotein involved in a number of biological processes such as such as bone formation, skin differentiation, cell proliferation, and promotes angiostasis. Pathologically, ECM1 contributes to the formation and metastasis of several types of cancer including breast, thyroid and hepatocellular cancers.(21128013) It inhibits MMP9 proteolytic activity.

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"