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Product Name
ESX1 antibody
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Description
ESX1 Rabbit Polyclonal antibody. Positive WB detected in mouse brain tissue. Positive IP detected in mouse brain tissue. Observed molecular weight by Western-blot: 65 kDa
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Tested applications
ELISA, WB, IP
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Species reactivity
Human, Mouse; other species not tested.
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Alternative names
ESX homeobox 1 antibody; ESX1 antibody; ESX1L antibody; ESX1R antibody; ESXR1 antibody; Homeobox protein ESX1 antibody
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Isotype
Rabbit IgG
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Preparation
This antibody was obtained by immunization of ESX1 recombinant protein (Accession Number: NM_153448). Purification method: Antigen affinity purified.
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Clonality
Polyclonal
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Formulation
PBS with 0.02% sodium azide and 50% glycerol pH 7.3.
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Storage instructions
Store at -20℃. DO NOT ALIQUOT
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Applications
Recommended Dilution:
WB: 1:200-1:2000
IP: 1:200-1:2000
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Validations
mouse brain tissue were subjected to SDS PAGE followed by western blot with Catalog No:110481(ESX1 antibody) at dilution of 1:800
IP Result of anti-ESX1 (IP:Catalog No:110481, 4ug; Detection:Catalog No:110481 1:500) with mouse brain tissue lysate 3440ug.
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Background
ESX1, also named as ESX1L and ESX1R , is an X-linked homeobox gene primarily expressed in the placenta and testis, with physiological functions in placenta/fetus development and spermatogenesis. It has a substantively different C-terminal region subject to strong purifying selection. ESX1 can be cleaved into 2 part: ESXR1-N(45kd) and ESXR1-C(20kd). ESXR1-N acts as a transcriptional repressor. ESXR1-C has the ability to inhibit cyclin turnover.
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