ESR2 Beta-3 antibody

ESR2 Beta-3 antibody

• DataSheet
• Material Safety Data Sheets (MSDS)

ESR2 Beta-3 Rabbit Polyclonal antibody. Positive IHC detected in human cervix tissue, human breast cancer tissue, human endometrial cancer tissue.

ELISA, IHC

Human; other species not tested.

ER BETA antibody; Erb antibody; ESR BETA antibody; ESR2 antibody; ESRB antibody; ESTRB antibody; estrogen receptor 2 (ER beta) antibody; Estrogen receptor beta antibody; NR3A2 antibody

Rabbit IgG

This antibody was obtained by immunization of Peptide (Accession Number: NM_001437). Purification method: Antigen affinity purified.

Polyclonal

PBS with 0.02% sodium azide and 50% glycerol pH 7.3.

Store at -20℃. DO NOT ALIQUOT

Estrogen receptor-beta (ESR2) is a member of the superfamily of nuclear receptors, which can transduce extracellular signals into transcriptional responses. It binds estrogens with an affinity similar to that of ESR1, and activates expression of reporter genes containing estrogen response elements (ERE) in an estrogen-dependent manner. DNA-binding by ESR1 and ESR2 is rapidly lost at 37 degrees Celsius in the absence of ligand while in the presence of 17 beta-estradiol and 4-hydroxy-tamoxifen loss in DNA-binding at elevated temperature is more gradual