ERBB3 antibody

Cat.#: 110402

Size:

Special Price 239.0 USD

Availability: In Stock
- +

Add to cart to get an online quotation

Product Information

  • Product Name
    ERBB3 antibody
  • Documents
  • Description
    ERBB3 Rabbit Polyclonal antibody. Positive IHC detected in human breast cancer tissue, human prostate cancer tissue. Observed molecular weight by Western-blot: 185kd
  • Tested applications
    ELISA, IHC
  • Species reactivity
    Human,Mouse,Rat; other species not tested.
  • Alternative names
    c erbB 3 antibody; c erbB3 antibody; ErbB 3 antibody; ERBB3 antibody; erbB3 S antibody; HER3 antibody; LCCS2 antibody; MDA BF 1 antibody; p180 ErbB3 antibody; p45 sErbB3 antibody; p85 sErbB3 antibody
  • Isotype
    Rabbit IgG
  • Preparation
    This antibody was obtained by immunization of ERBB3 recombinant protein (Accession Number: BC002706). Purification method: Antigen affinity purified.
  • Clonality
    Polyclonal
  • Formulation
    PBS with 0.1% sodium azide and 50% glycerol pH 7.3.
  • Storage instructions
    Store at -20℃. DO NOT ALIQUOT
  • Applications

    Recommended Dilution:

    IHC: 1:20-1:200

  • Validations

    Immunohistochemical of paraffin-embedded human prostate cancer using Catalog No:110402(ERBB3 antibody) at dilution of 1:10 (under 40x lens)

    Immunohistochemical of paraffin-embedded human prostate cancer using Catalog No:110402(ERBB3 antibody) at dilution of 1:10 (under 40x lens)

    Immunohistochemistry of paraffin-embedded human breast cancer tissue slide using Catalog No:110402(ERBB3 Antibody) at dilution of 1:200 (under 10x lens)

    Immunohistochemistry of paraffin-embedded human breast cancer tissue slide using Catalog No:110402(ERBB3 Antibody) at dilution of 1:200 (under 10x lens)

    Immunohistochemistry of paraffin-embedded human breast cancer tissue slide using Catalog No:110402(ERBB3 Antibody) at dilution of 1:200 (under 40x lens)

    Immunohistochemistry of paraffin-embedded human breast cancer tissue slide using Catalog No:110402(ERBB3 Antibody) at dilution of 1:200 (under 40x lens)

  • Background
    V-erb-b2 erythroblastic leukemia viral oncogene homolog 3 (ErbB-3, HER3) is a member of the EGF receptor tyrosine kinase family including EGFR (HER1), Neu (ErbB-2, HER2), ErbB-3 (HER3), and ErbB-4 (HER4) that are frequently overexpressed in a variety of carcinomas. These family members form either homodimers or heterodimers upon ligand binding to mediate cell growth. ErbB-3 binds and is activated by neuregulins and NTAK. It forms a heterodimer with each of the other ErbB receptors. ErbB-3 is predominantly expressed in epithelial tissues and brain, and is overexpressed in a subset of human mammary tumors.

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"