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Product Name
Human E-Selectin/CD62e/SELE (His Tag) recombinant protein
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Description
Cell-surface glycoprotein having a role in immunoadhesion. Mediates in the adhesion of blood neutrophils in cytokine-activated endothelium through interaction with PSGL1/SELPLG. May have a role in capillary morphogenesis.
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Protein name
E-selectin
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Protein short names
CD62E; LECAM2; E-SELECTIN; SELE; ELAM1; ESEL; ELAM; ELAM-1; RP1-117P20.2
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Uniprot ID
P16581
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Gene Name
SELE; ELAM1
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Source/Expression Host
Human Cells
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Expression Plasmid/cDNA
A DNA sequence encoding the extracellular domain (Met 1-Pro 556) of human CD62E (NP_000441.2) precursor was expressed with the fused C-terminal polyhistidine tag.
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Protein Species
Human
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Molecular weight
The recombinant human CD62E comprises 546 amino acids after removal of the signal peptide and has a predicted molecular mass of 60 kDa. In SDS-PAGE under reducing conditions, the apparent molecular mass of rh CD62E is approximately 110 kDa due to glycosylation.
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Purity
> 97 % as determined by SDS-PAGE
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Validations
Human E-Selectin / CD62e / SELE Protein (His Tag) SDS-PAGE
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