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Product Name
Mouse E-Selectin/CD62e/SELE recombinant protein
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Description
Cell-surface glycoprotein having a role in immunoadhesion. Mediates in the adhesion of blood neutrophils in cytokine-activated endothelium through interaction with PSGL1/SELPLG. May have a role in capillary morphogenesis.
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Protein name
E-selectin
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Protein short names
E-SELECTIN; LECAM2; ELAM1; SELE; CD62E; ESEL; RP1-117P20.2; ELAM-1; ELAM
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Uniprot ID
Q3U5F6
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Gene Name
Sele; Elam-1
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Source/Expression Host
Human Cells
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Expression Plasmid/cDNA
A DNA sequence encoding the mouse SELE (NP_035475.1)(Met1-Pro564) was expressed with six amino acids (LEVLFQ) at the C-terminus.
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Protein Species
Mouse
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Molecular weight
The recombinant mouse SELE comprises 543 amino acids and has a predicted molecular mass of 59.3 kDa. The apparent molecular mass of the protein is approximately 70 kDa in SDS-PAGE under reducing conditions due to glycosylation.
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Purity
> 90 % as determined by SDS-PAGE
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Activity
Measured by the ability of the immobilized protein to support the adhesion of U937 cells.
When 5 x 10E4 cells/well are added to SELE coated plates (2 μg/mL and 100 μL/well), approximately >70% cells will adhere specifically after 60 minutes at 37℃. -
Validations
Mouse E-Selectin / CD62e / SELE Protein SDS-PAGE
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