Dynamitin antibody

Dynamitin antibody

• DataSheet
• Material Safety Data Sheets (MSDS)

Dynamitin Mouse Monoclonal antibody. Positive WB detected in human brain tissue. Positive IHC detected in human gliomas tissue. Observed molecular weight by Western-blot: 52+150kd

ELISA, WB, IHC

Human,Mouse; other species not tested.

DCTN2 antibody; dynactin 2 antibody; dynactin 2 (p50) antibody; Dynactin subunit 2 antibody; Dynamitin antibody

Mouse IgG3

This antibody was obtained by immunization of Dynamitin recombinant protein (Accession Number: NM_001261413). Purification method: Protein A purified.

Monoclonal

PBS with 0.02% sodium azide and 50% glycerol pH 7.3.

Store at -20℃. DO NOT ALIQUOT

Dynamitin is a 50 kDa protein containing a calmodulin binding domain, a putative ATPase domain and MacMARCKS-binding domain. This protein is a part of the dynactin complex believed to link the dynactin complex to membrane compartments. Its functions are tightly associated with dynein motor protein, thus extend to vesicle trafficking and membrane integrity. Dynamitin was named so because its overexpression causes dynactin complex which contains 10 subunits, to disassemble. Its N terminal 58 amino acid is for MacMARCKS binding and residues 59-83 is responsible for calmodulin binding. This antibody is is against the N terminal 86aa of full length p50 dynamitin.