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Product Name
Desmocollin 2 antibody
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Description
Desmocollin 2 Mouse Monoclonal antibody. Positive WB detected in 293 cells. Observed molecular weight by Western-blot: 110 kDa
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Tested applications
ELISA, WB
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Species reactivity
Human,Mouse; other species not tested.
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Alternative names
ARVD11 antibody; Cadherin family member 2 antibody; CDHF2 antibody; desmOCollin 2 antibody; DesmOCollin 3 antibody; Desmosomal glycoprotein II antibody; Desmosomal glycoprotein III antibody; DG2 antibody; DGII/III antibody; DKFZp686I11137 antibody; DSC2 antibody; DSC3 antibody
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Isotype
Mouse IgG2a
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Preparation
This antibody was obtained by immunization of Desm℃ollin 2 recombinant protein (Accession Number: NM_024422). Purification method: Protein A purified.
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Clonality
Monoclonal
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Formulation
PBS with 0.02% sodium azide and 50% glycerol pH 7.3.
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Storage instructions
Store at -20℃. DO NOT ALIQUOT
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Applications
Recommended Dilution:
WB: 1:500-1:5000
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Validations
HEK-293 cells were subjected to SDS PAGE followed by western blot with Catalog No:107240(DSC2 antibody) at dilution of 1:1000
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Background
Desmocollin 2 (DSC2) is a member of the desmocollin subfamily of the cadherin superfamily. The desmocollins (DSC1-3), along with the desmogleins (DSG1-4), are found primarily in epithelia and cardiac muscle where they constitute the adhesive proteins of the intercellular desmosome junctions and are required for cell adhesion and desmosome formation. Mutations in DSC2 gene are associated with arrhythmogenic right ventricular dysplasia-11.
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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"