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Product Name
Desmin antibody
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Description
Desmin Rabbit Polyclonal antibody. Positive IHC detected in human heart tissue, human skeletal muscle tissue, mouse heart tissue. Positive WB detected in mouse heart tissue, mouse skeletal muscle tissue, rat skeletal muscle tissue. Observed molecular weight by Western-blot: 50-55 kDa
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Tested applications
ELISA, WB, IHC
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Species reactivity
Human, Mouse, Rat; other species not tested.
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Alternative names
CMD1I antibody; CSM1 antibody; CSM2 antibody; DES antibody; desmin antibody; FLJ12025 antibody; FLJ39719 antibody; FLJ41013 antibody; FLJ41793 antibody
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Isotype
Rabbit IgG
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Preparation
This antibody was obtained by immunization of Desmin recombinant protein (Accession Number: NM_001927). Purification method: Antigen affinity purified.
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Clonality
Polyclonal
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Formulation
PBS with 0.02% sodium azide and 50% glycerol pH 7.3.
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Storage instructions
Store at -20℃. DO NOT ALIQUOT
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Applications
Recommended Dilution:
WB: 1:200-1:2000
IHC: 1:20-1:200
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Validations
mouse heart tissue were subjected to SDS PAGE followed by western blot with Catalog No:109896(DES Antibody) at dilution of 1:600
Immunohistochemistry of paraffin-embedded human heart tissue slide using Catalog No:109896(DES Antibody) at dilution of 1:50 (under 10x lens)
Immunohistochemistry of paraffin-embedded human heart tissue slide using Catalog No:109896(DES Antibody) at dilution of 1:50 (under 40x lens)
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Background
Desmin is the main intermediate filament protein in skeletal and cardiac muscle cells and is essential for both the structural integrity and the survival of muscle cells. As an abundant muscle-specific protein, desmin has been widely used as a marker of muscle derived tumors. Anti-desmin is also valuable in the differential diagnosis of tumors of uncertain origin.
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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"