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Product Name
DcR2 antibody
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Description
DcR2 Rabbit Polyclonal antibody. Positive WB detected in Apoptosised HeLa cells, A549 cells, HeLa cells. Positive IHC detected in human kidney tissue. Observed molecular weight by Western-blot: 47-50 kDa
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Tested applications
ELISA, WB, IHC
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Species reactivity
Human; other species not tested.
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Alternative names
CD264 antibody; DCR2 antibody; Decoy receptor 2 antibody; TNFRSF10D antibody; TRAIL R4 antibody; TRAIL receptor 4 antibody; TRAILR4 antibody; TRUNDD antibody
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Isotype
Rabbit IgG
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Preparation
This antibody was obtained by immunization of DcR2 recombinant protein (Accession Number: NM_003840). Purification method: Antigen affinity purified.
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Clonality
Polyclonal
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Formulation
PBS with 0.02% sodium azide and 50% glycerol pH 7.3.
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Storage instructions
Store at -20℃. DO NOT ALIQUOT
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Applications
Recommended Dilution:
WB: 1:500-1:5000
IHC: 1:20-1:200
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Validations
Apoptosised HeLa cells were subjected to SDS PAGE followed by western blot with Catalog No:109756(TRAILR4 antibody) at dilution of 1:300
Immunohistochemical of paraffin-embedded human kidney using Catalog No:109756(TRAILR4 antibody) at dilution of 1:50 (under 10x lens)
Immunohistochemical of paraffin-embedded human kidney using Catalog No:109756(TRAILR4 antibody) at dilution of 1:50 (under 40x lens)
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Background
TNFRSF10D represents tumor necrosis factor receptor superfamily, member 10d, decoy with truncated death domain
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References
- Fu K, Ren H, Wang Y, Fei E, Wang H, Wang G. DJ-1 inhibits TRAIL-induced apoptosis by blocking pro-caspase-8 recruitment to FADD. Oncogene. 31(10):1311-22. 2012.
- Xu Y, Zhang S, Niu H. STIM1 accelerates cell senescence in a remodeled microenvironment but enhances the epithelial-to-mesenchymal transition in prostate cancer. Scientific reports. 5:11754. 2015.
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