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Product Name
CRP antibody
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Description
CRP Rabbit Polyclonal antibody. Positive IHC detected in human liver tissue. Positive WB detected in serum from mouse injected with bacteria. Observed molecular weight by Western-blot: 25 kDa
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Tested applications
ELISA, WB, IHC
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Species reactivity
Human, Mouse; other species not tested.
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Alternative names
C reactive protein antibody; CRP antibody; PTX1 antibody
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Isotype
Rabbit IgG
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Preparation
This antibody was obtained by immunization of CRP recombinant protein (Accession Number: NM_000567). Purification method: Antigen Affinity purified.
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Clonality
Polyclonal
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Formulation
PBS with 0.02% sodium azide and 50% glycerol pH 7.3.
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Storage instructions
Store at -20℃. DO NOT ALIQUOT
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Applications
Recommended Dilution:
WB: 1:200-1:2000
IHC: 1:50-1:500
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Validations
Serum from mouse injected with bacteria were subjected to SDS PAGE followed by western blot with Catalog No:109578(CRP Antibody) at dilution of 1:600
Immunohistochemistry of paraffin-embedded human liver tissue slide using Catalog No:109578(CRP Antibody) at dilution of 1:200 (under 10x lens).
Immunohistochemistry of paraffin-embedded human liver tissue slide using Catalog No:109578(CRP Antibody) at dilution of 1:200 (under 40x lens).
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Background
C-reactive protein (CRP) is an acute-phase serum protein synthesized by the liver in response to interleukin-6 (IL-6) during inflammation. The name of CRP derives from its ability to react with the C polysaccharide of Streptococcus pneumoniae. CRP is an annular, pentameric protein that belongs to the pentraxin family of proteins. CRP displays several functions associated with host defense: it promotes agglutination, bacterial capsular swelling, phagocytosis and complement fixation through its calcium-dependent binding to phosphorylcholine. It is used mainly as a marker of inflammation.
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