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Product Name
CRMP5 antibody
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Description
CRMP5 Rabbit Polyclonal antibody. Positive WB detected in mouse brain tissue. Positive IHC detected in human prostate cancer tissue. Observed molecular weight by Western-blot: 61kd
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Tested applications
ELISA, WB, IHC
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Species reactivity
Human,Mouse,Rat; other species not tested.
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Alternative names
CRAM antibody; CRMP 5 antibody; CRMP3 assOCiated molecule antibody; CRMP5 antibody; dihydropyrimidinase like 5 antibody; DPYSL5 antibody; DRP 5 antibody; FLJ45383 antibody; ULIP 6 antibody; Ulip6 antibody; UNC33 like phosphoprotein 6 antibody
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Isotype
Rabbit IgG
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Preparation
This antibody was obtained by immunization of CRMP5 recombinant protein (Accession Number: NM_020134). Purification method: Antigen affinity purified.
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Clonality
Polyclonal
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Formulation
PBS with 0.1% sodium azide and 50% glycerol pH 7.3.
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Storage instructions
Store at -20℃. DO NOT ALIQUOT
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Applications
Recommended Dilution:
WB: 1:500-1:5000
IHC: 1:20-1:200
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Validations
mouse brain tissue were subjected to SDS PAGE followed by western blot with Catalog No:109574(DPYSL5 antibody) at dilution of 1:1000
Immunohistochemical of paraffin-embedded human prostate cancer using Catalog No:109574(DPYSL5 antibody) at dilution of 1:100 (under 25x lens)
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Background
DPYSL5(Dihydropyrimidinase-related protein 5) is also named as CRMP5, ULIP6 and belongs to the hydantoinase/dihydropyrimidinase subfamily. It may have a function in neuronal differentiation and/or axon growth. SCLCs universally express CRMP5 and in thymoma, none of the CRMPs are detected by immunohistochemistry in tumorous epithelial cells with specific antibodies including CRMP5.The normal CRMP5 is probably not expressed by tumorous epithelial cells.(PMID:16519949).
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References
- Bae N, Wang Y, Li L, Rayport S, Lubec G. Network of brain protein level changes in glutaminase deficient fetal mice. Journal of proteomics. 80:236-49. 2013.
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