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Product Name
CRMP4 antibody
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Description
CRMP4 Rabbit Polyclonal antibody. Positive IHC detected in mouse brain tissue, human heart tissue. Positive WB detected in mouse cerebellum tissue, mouse brain tissue. Observed molecular weight by Western-blot: 60-70kd
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Tested applications
ELISA, WB, IHC
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Species reactivity
Human,Mouse,Rat; other species not tested.
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Alternative names
CRMP 4 antibody; CRMP4 antibody; dihydropyrimidinase like 3 antibody; DPYSL3 antibody; DRP 3 antibody; DRP3 antibody; LCRMP antibody; ULIP antibody; ULIP 1 antibody; ULIP1 antibody; Unc 33 like phosphoprotein 1 antibody
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Isotype
Rabbit IgG
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Preparation
This antibody was obtained by immunization of CRMP4 recombinant protein (Accession Number: NM_001387). Purification method: Antigen affinity purified.
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Clonality
Polyclonal
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Formulation
PBS with 0.02% sodium azide and 50% glycerol pH 7.3.
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Storage instructions
Store at -20℃. DO NOT ALIQUOT
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Applications
Recommended Dilution:
WB: 1:500-1:5000
IHC: 1:20-1:200
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Validations
mouse cerebellum tissue were subjected to SDS PAGE followed by western blot with Catalog No:109572(DPYSL3 antibody) at dilution of 1:400
Immunohistochemistry of paraffin-embedded mouse brain tissue slide using Catalog No:109572(DPYSL3 Antibody) at dilution of 1:50 (under 10x lens)
Immunohistochemistry of paraffin-embedded mouse brain tissue slide using Catalog No:109572(DPYSL3 Antibody) at dilution of 1:50 (under 40x lens)
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Background
DPYSL3(Dihydropyrimidinase-related protein 3) is also named as CRMP4, DRP3, ULIP, ULIP1 and belongs to the hydantoinase/dihydropyrimidinase subfamily.DPYSL3 is a developmentally regulated protein, strongly expressed in early embryonic post-mitotic neural cells, reaching a peak of expression around the first post-natal week. In the adult brain, DPYSL3 is present mainly in regions that retain neurogenesis.DPYSL3 protein is also found in synaptic sites at the adult neuromuscular junction where it may be involved in the maintenance of neuronal stability(PMID: 16135096).It has 2 isoforms produced by alternative splicing.
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