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Product Name
CPT1A antibody
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Description
CPT1A Mouse Monoclonal antibody. Positive IHC detected in human heart tissue, human liver tissue. Positive WB detected in lo2 cells, MCF7 cells. Positive IP detected in MCF-7 cells. Observed molecular weight by Western-blot: 86kD
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Tested applications
ELISA, WB, IHC, IP
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Species reactivity
Human, Mouse, Rat; other species not tested.
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Alternative names
CPT I antibody; CPT1 antibody; CPT1 L antibody; CPT1A antibody; CPTI L antibody; L CPT1 antibody
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Isotype
Mouse IgG2a
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Preparation
This antibody was obtained by immunization of CPT1A recombinant protein (Accession Number: NM_001031847). Purification method: Protein A purified.
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Clonality
Monoclonal
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Formulation
PBS with 0.02% sodium azide and 50% glycerol pH 7.3.
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Storage instructions
Store at -20℃. DO NOT ALIQUOT
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Applications
Recommended Dilution:
WB: 1:200-1:2000
IP: 1:200-1:2000
IHC: 1:20-1:200
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Validations
L02 cells were subjected to SDS PAGE followed by western blot with Catalog No:107173(CPT1A antibody) at dilution of 1:500
Immunohistochemical of paraffin-embedded human heart using Catalog No:107173(CPT1A antibody) at dilution of 1:50 (under 10x lens)
Immunohistochemical of paraffin-embedded human heart using Catalog No:107173(CPT1A antibody) at dilution of 1:50 (under 40x lens)
IP Result of anti-CPT1A (IP:Catalog No:107173, 4ug; Detection:Catalog No:107173 1:500) with MCF-7 cells lysate 1200ug.
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Background
CPT1A, also named as CPT1, CPT1-L and L-CPTI, belongs to the carnitine/choline acetyltransferase family. It is Localized Chromosome 11q13.1-2. Carnitine palmitoyltransferase (CPT) deficiencies are common disorders of mitochondrial fatty acid oxidation. The CPT system is made up of two separate proteins located in the outer (CPT1) and inner (CPT2) mitochondrial membranes. CPT1A is an active forms of related liver-type carnitine palmitoyltransferase I. (PMID: 11001805). CPT1A deficiency presents as recurrent attacks of fasting hypoketotic hypoglycemia. (PMID: 15363638). This antibody can bind the close sequences genes.
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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"