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Product Name
Complement factor B antibody
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Description
Complement factor B Rabbit Polyclonal antibody. Positive IHC detected in human liver tissue. Positive WB detected in human serum tissue, human blood tissue. Observed molecular weight by Western-blot: 93-100 kDa, 60-69 kDa
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Tested applications
ELISA, WB, IHC
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Species reactivity
Human; other species not tested.
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Alternative names
BFD antibody; C3/C5 convertase antibody; CFAB antibody; CFB antibody; Complement factor B antibody; FBI12 antibody; GBG antibody; Glycine rich beta glycoprotein antibody; H2 Bf antibody; PBF2 antibody; Properdin factor B antibody
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Isotype
Rabbit IgG
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Preparation
This antibody was obtained by immunization of Complement factor B recombinant protein (Accession Number: NM_001710). Purification method: Antigen affinity purified.
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Clonality
Polyclonal
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Formulation
PBS with 0.1% sodium azide and 50% glycerol pH 7.3.
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Storage instructions
Store at -20℃. DO NOT ALIQUOT
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Applications
Recommended Dilution:
WB: 1:200-1:2000
IHC: 1:20-1:200
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Validations
human serum tissue were subjected to SDS PAGE followed by western blot with Catalog No:109446(CFB antibody) at dilution of 1:800
Immunohistochemistry of paraffin-embedded human liver tissue slide using Catalog No:109446(CFB Antibody) at dilution of 1:50 (under 10x lens)
Immunohistochemistry of paraffin-embedded human liver tissue slide using Catalog No:109446(CFB Antibody) at dilution of 1:50 (under 40x lens)
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Background
Complement factor B (CFB) is a component of the alternative pathway of complement activation. Complement factor B is cleaved into Ba and Bb by factor D in the presence of C3b. The active subunit Bb is a serine protease which associates with C3b to form the alternative pathway C3 convertase. Bb is involved in the proliferation of preactivated B lymphocytes, while Ba inhibits their proliferation.
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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"