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Product Name
Human Complement component 7 (Fc Tag) recombinant protein
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Description
Constituent of the membrane attack complex (MAC) that plays a key role in the innate and adaptive immune response by forming pores in the plasma membrane of target cells. C7 serves as a membrane anchor.
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Protein name
Complement component C7
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Protein short names
GM1238; COMPLEMENT COMPONENT C7; A530026G17
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Uniprot ID
P10643
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Gene Name
C7
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Source/Expression Host
Human Cells
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Expression Plasmid/cDNA
A DNA sequence encoding the human C7 (P10643) (Met1-Gln843) was expressed, fused with the Fc region of human IgG1 at the C-terminus.
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Protein Species
Human
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Molecular weight
The recombinant human C7 /Fc is a disulfide-linked homodimer. The reduced monomer comprises 1062 amino acids and has a predicted molecular mass of 118 kDa. The apparent molecular mass of the protein is approximately 118 kDa in SDS-PAGE under reducing conditions.
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Purity
> 90 % as determined by SDS-PAGE
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Validations
Human C7 / Complement component 7 Protein (Fc Tag) SDS-PAGE
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