-
Product Name
CNPase antibody
- Documents
-
Description
CNPase Rabbit Polyclonal antibody. Positive IHC detected in mouse brain tissue. Positive WB detected in HepG2 cells. Observed molecular weight by Western-blot: 48 kDa
-
Tested applications
ELISA, WB, IHC
-
Species reactivity
Human,Mouse,Rat; other species not tested.
-
Alternative names
CNP antibody; CNP1 antibody; CNPase antibody
- Immunogen
-
Isotype
Rabbit IgG
-
Preparation
This antibody was obtained by immunization of CNPase recombinant protein (Accession Number: NM_033133). Purification method: Antigen affinity purified.
-
Clonality
Polyclonal
-
Formulation
PBS with 0.02% sodium azide and 50% glycerol pH 7.3.
-
Storage instructions
Store at -20℃. DO NOT ALIQUOT
-
Applications
Recommended Dilution:
WB: 1:500-1:5000
IHC: 1:20-1:200
-
Validations
HepG2 cells were subjected to SDS PAGE followed by western blot with Catalog No:109355(CNP antibody) at dilution of 1:500
Immunohistochemistry of paraffin-embedded mouse brain tissue slide using Catalog No:109355(CNP Antibody) at dilution of 1:50 (under 10x lens)
Immunohistochemistry of paraffin-embedded mouse brain tissue slide using Catalog No:109355(CNP Antibody) at dilution of 1:50 (under 40x lens)
-
Background
CNP(2',3'-cyclic-nucleotide 3'-phosphodiesterase) belongs to the cyclic nucleotide phosphodiesterase family. It plays an essential role in axonal survival but not in myelin assembly, coupling oligodendroglial functions in axonal support and myelination. This protein has 2 isoforms produced by alternative splicing.
-
References
- Ma H, Zhao XL, Wang XY. 2',3'-cyclic nucleotide 3'-phosphodiesterases inhibit hepatitis B virus replication. PloS one. 8(11):e80769. 2013.
Related Products / Services
Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"