-
Product Name
Chromogranin A antibody
- Documents
-
Description
Chromogranin A Rabbit Polyclonal antibody. Positive IHC detected in human pancreas tissue, human colon tissue, human lung cancer tissue, human small intestine tissue, mouse colon tissue.
-
Tested applications
ELISA, IHC
-
Species reactivity
Human; other species not tested.
-
Alternative names
CGA antibody; CHGA antibody; Chromogranin A antibody; Pituitary secretory protein I antibody; SP I antibody; Vasostatin I Vasostatin 2 antibody
-
Isotype
Rabbit IgG
-
Preparation
This antibody was obtained by immunization of Chromogranin A recombinant protein (Accession Number: NM_001275). Purification method: Antigen affinity purified.
-
Clonality
Polyclonal
-
Formulation
PBS with 0.02% sodium azide and 50% glycerol pH 7.3.
-
Storage instructions
Store at -20℃. DO NOT ALIQUOT
-
Applications
Recommended Dilution:
IHC: 1:20-1:200
-
Validations
Immunohistochemical of paraffin-embedded human pancreas using Catalog No:109288(CHGA antibody) at dilution of 1:400 (under 10x lens)
Immunohistochemical of paraffin-embedded human pancreas using Catalog No:109288(CHGA antibody) at dilution of 1:400 (under 40x lens)
Immunohistochemical of paraffin-embedded human colon using Catalog No:109288(CHGA antibody) at dilution of 1:800 (under 10x lens)
Immunohistochemical of paraffin-embedded human colon using Catalog No:109288(CHGA antibody) at dilution of 1:800 (under 40x lens)
Immunohistochemical of paraffin-embedded human small intestine using Catalog No:109288(CHGA antibody) at dilution of 1:800 (under 10x lens)
Immunohistochemical of paraffin-embedded human small intestine using Catalog No:109288(CHGA antibody) at dilution of 1:800 (under 40x lens)
-
Background
Chromogranin A is a member of the granin family of neuroendocrine secretory proteins. It is located in secretory vesicles of neurons and endocrine cells. Chromogranin A is the precursor to several functional peptides including vasostatin, pancreastatin, catestatin and parastatin. These peptides negatively modulate the neuroendocrine function of the releasing cell (autocrine) or nearby cells (paracrine). CgA is one of the most used tumor markers in NET's (neuroendocrine tumors) , and elevated CgA concentrations have been demonstrated in serum or plasma of patients with different types of these tumors.
Related Products / Services
Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"