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Product Name
Mouse CDNF/ARMETL1 (His Tag) recombinant protein
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Description
Trophic factor for dopamine neurons. Prevents the 6-hydroxydopamine (6-OHDA)-induced degeneration of dopaminergic neurons. When administered after 6-OHDA-lesioning, restores the dopaminergic function and prevents the degeneration of dopaminergic neurons in substantia nigra (By similarity).
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Protein name
Cerebral dopamine neurotrophic factor
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Protein short names
RP24-129J15.1; CDNF; MGC129430; ARMETL1; 9330140G23
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Uniprot ID
Q8CC36
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Gene Name
Cdnf; Armetl1
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Source/Expression Host
Human Cells
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Expression Plasmid/cDNA
A DNA sequence encoding the mouse CDNF (NP_808315.1) (Met 1-Leu 187) was expressed, with a polyhistidine tag at the C-terminus.
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Protein Species
Mouse
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Molecular weight
The secreted recombinant mouse CDNF consists of 174 amino acids and migrates as an approximately 20 kDa band in SDS-PAGE under reducing conditions as predicted.
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Purity
> 95 % as determined by SDS-PAGE
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Validations
Mouse CDNF / ARMETL1 Protein (His Tag) SDS-PAGE
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