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Product Name
Human CDNF/ARMETL1 (Fc Tag) recombinant protein
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Description
Trophic factor for dopamine neurons. Prevents the 6-hydroxydopamine (6-OHDA)-induced degeneration of dopaminergic neurons. When administered after 6-OHDA-lesioning, restores the dopaminergic function and prevents the degeneration of dopaminergic neurons in substantia nigra (By similarity).
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Protein name
Cerebral dopamine neurotrophic factor
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Protein short names
RP24-129J15.1; CDNF; 9330140G23; MGC129430; ARMETL1
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Uniprot ID
Q49AH0
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Gene Name
CDNF; ARMETL1
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Source/Expression Host
Human Cells
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Expression Plasmid/cDNA
A DNA sequence encoding the human CDNF (NP_001025125.2) (Met1-Leu187) was expressed with the Fc region of human IgG1 at the C-terminus.
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Protein Species
Human
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Molecular weight
The recombinant human CDNF consists 401 amino acids and predicts a molecular mass of 45.2 kDa.
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Purity
> 95 % as determined by SDS-PAGE.
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Validations
Human CDNF / ARMETL1 Protein (Fc Tag) SDS-PAGE
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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"