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Product Name
CDC14A Polyclonal Antibody
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Description
Polyclonal antibody to CDC14A
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Tested applications
WB, IHC, FC
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Species reactivity
Human, Mouse
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Alternative names
CDC14A antibody; DFNB105 antibody; cdc14 antibody; hCDC14 antibody; cell division cycle 14A antibody
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Isotype
Rabbit IgG
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Preparation
Antigen: A synthetic Peptide of human CDC14A
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Clonality
Polyclonal
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Formulation
PBS with 0.02% sodium azide, pH7.3.
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Storage instructions
Store at 4℃. Avoid freeze / thaw cycles.
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Applications
WB 1:500 - 1:1000
IHC 1:20 - 1:50
FC 1:20 - 1:50 -
Validations
Western blot - CDC14A Polyclonal Antibody
Western blot analysis of extracts of HepG2 cells, using CDC14A antibody .Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) at 1:10000 dilution.Lysates/proteins: 25ug per lane.Blocking buffer: 3% nonfat dry milk in TBST.
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Background
Dual-specificity phosphatase. Required for centrosome separation and productive cytokinesis during cell division. Dephosphorylates SIRT2 around early anaphase. May dephosphorylate the APC subunit FZR1/CDH1, thereby promoting APC-FZR1 dependent degradation of mitotic cyclins and subsequent exit from mitosis. Required for normal hearing.
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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"