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Product Name
CD46 antibody
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Description
CD46 Rabbit Polyclonal antibody. Positive IHC detected in human colon cancer tissue, human breast cancer tissue. Positive IP detected in A549 cells. Positive WB detected in A549 cells, mouse thymus tissue. Observed molecular weight by Western-blot: 50-56 kDa
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Tested applications
ELISA, WB, IP, IHC
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Species reactivity
Human, Mouse; other species not tested.
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Alternative names
CD46 antibody; MCP antibody; Membrane cofactor protein antibody; MIC10 antibody; TLX antibody; TRA2.10 antibody
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Isotype
Rabbit IgG
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Preparation
This antibody was obtained by immunization of CD46 recombinant protein (Accession Number: NM_153826). Purification method: Antigen affinity purified.
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Clonality
Polyclonal
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Formulation
PBS with 0.1% sodium azide and 50% glycerol pH 7.3.
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Storage instructions
Store at -20℃. DO NOT ALIQUOT
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Applications
Recommended Dilution:
WB: 1:500-1:5000
IP: 1:500-1:5000
IHC: 1:50-1:500
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Validations
A549 cells were subjected to SDS PAGE followed by western blot with Catalog No:109126(CD46 antibody) at dilution of 1:400
IP Result of anti-CD46 (IP:Catalog No:109126, 4ug; Detection:Catalog No:109126 1:1000) with A549 cells lysate 1800ug.
Immunohistochemistry of paraffin-embedded human colon cancer tissue slide using Catalog No:109126(CD46 Antibody) at dilution of 1:200 (under 10x lens). heat mediated antigen retrieved with Tris-EDTA buffer(pH9).
Immunohistochemistry of paraffin-embedded human colon cancer tissue slide using Catalog No:109126(CD46 Antibody) at dilution of 1:200 (under 40x lens). heat mediated antigen retrieved with Tris-EDTA buffer(pH9).
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Background
CD46 represents CD46 molecule, complement regulatory protein
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References
- Mohlin FC, Nilsson SC, Levart TK. Functional characterization of two novel non-synonymous alterations in CD46 and a Q950H change in factor H found in atypical hemolytic uremic syndrome patients. Molecular immunology. 65(2):367-76. 2015.
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