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Product Name
CCHCR1 antibody
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Description
CCHCR1 Rabbit Polyclonal antibody. Positive WB detected in Transfected HEK-293 cells. Positive IF detected in HEK-293 cells. Positive IHC detected in human testis tissue, human skin tissue. Observed molecular weight by Western-blot: 85 kDa
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Tested applications
ELISA, WB, IHC, IF
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Species reactivity
Human; other species not tested.
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Alternative names
C6orf18 antibody; CCHCR1 antibody; HCR antibody; Pg8 antibody; Putative gene 8 protein antibody; SBP antibody
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Isotype
Rabbit IgG
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Preparation
This antibody was obtained by immunization of CCHCR1 recombinant protein (Accession Number: XM_011514705). Purification method: Antigen affinity purified.
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Clonality
Polyclonal
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Formulation
PBS with 0.02% sodium azide and 50% glycerol pH 7.3.
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Storage instructions
Store at -20℃. DO NOT ALIQUOT
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Applications
Recommended Dilution:
WB: 1:500-1:5000
IHC: 1:20-1:200
IF: 1:20-1:200
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Validations
Transfected HEK-293 cells were subjected to SDS PAGE followed by western blot with Catalog No:108995(CCHCR1 Antibody) at dilution of 1:1000
Immunohistochemistry of paraffin-embedded human testis tissue slide using Catalog No:108995(CCHCR1 Antibody) at dilution of 1:50 (under 10x lens)
Immunohistochemistry of paraffin-embedded human testis tissue slide using Catalog No:108995(CCHCR1 Antibody) at dilution of 1:50 (under 40x lens)
Immunofluorescent analysis of HEK-293 cells using Catalog No:108995(CCHCR1 Antibody) at dilution of 1:50 and Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L)
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Background
CCHCR1, also named as C6orf18 or Putative gene 8 protein, is a 782 amino acid protein, which is a nuclear protein abundantly expressed in heart, liver, skeletal muscle, kidney and pancreas, and to a lesser extent in lung and placenta. HCR is overexpressed in keratinocytes of psoriatic lesions. HCR is associated with susceptibility to psoriasis, a chronic inflammatory dermatosis that affects approximately 2% of the population. CCHCR1 may be a regulator of keratinocyte proliferation or differentiation.
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