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Product Name
CAV3 Monoclonal Antibody
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Description
Monoclonal antibody to CAV3
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Tested applications
WB, IP
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Species reactivity
Human, Mouse, Rat
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Alternative names
CAV3 antibody; LGMD1C antibody; LQT9 antibody; VIP-21 antibody; VIP21 antibody; caveolin-3 antibody
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Isotype
Rabbit IgG
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Preparation
Antigen: Recombinant protein of human CAV3
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Clonality
Monoclonal
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Formulation
PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
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Storage instructions
Store at -20℃. Avoid freeze / thaw cycles.
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Applications
WB 1:500 - 1:2000
IP 1:20 - 1:50 -
Validations
Western blot - CAV3 Monoclonal Antibody
Western blot analysis of extracts of various cell lines, using CAV3 antibody .Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) at 1:10000 dilution.Lysates/proteins: 25ug per lane.Blocking buffer: 3% nonfat dry milk in TBST.
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Background
May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity. May also regulate voltage-gated potassium channels. Plays a role in the sarcolemma repair mechanism of both skeletal muscle and cardiomyocytes that permits rapid resealing of membranes disrupted by mechanical stress (By similarity). Mediates the recruitment of CAVIN2 and CAVIN3 proteins to the caveolae.
Related Products / Services
Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"