• Human Cathepsin S/CTSS (His Tag) recombinant protein

Human Cathepsin S/CTSS (His Tag) recombinant protein

Cat.#: 501120

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Product Information

  • Product Name
    Human Cathepsin S/CTSS (His Tag) recombinant protein
  • Documents
  • Description
    Thiol protease. Key protease responsible for the removal of the invariant chain from MHC class II molecules. The bond-specificity of this proteinase is in part similar to the specificities of cathepsin L and cathepsin N.
  • Protein name
    Cathepsin S
  • Protein short names
    CAT S; CTSS; CATHEPSIN S; MGC3886
  • Uniprot ID
    P25774
  • Gene Name
    CTSS
  • Source/Expression Host
    Human Cells
  • Expression Plasmid/cDNA
    A DNA sequence encoding the pro form of human CTSS (NP_004070.3) (Met 1-Ile 331) with a carboxy-terminal polyhistidine tag was expressed.
  • Protein Species
    Human
  • Molecular weight
    The secreted recombinant human CTSS consists of 326 amino acids with the predicted molecular mass of 37 kDa as estimated by SDS-PAGE under reducing conditions.
  • Purity
    > 97 % as determined by SDS-PAGE
  • Activity
    Measured by its ability to cleave a fluorogenic peptide substrate, (7-methoxycoumarin-4-yl) acetyl-Arg-Pro-Lys-Pro-Val-Glu-Nva-Trp-Arg-Lys (2, 4-dinitrophenyl)-NH2 (R&D Systems, Catalog#ES002). Cleavage of ES002 can be measured using excitation and emission wavelengths at 320 nm and 405 nm, respectively. The specific activity is >300 pmoles/min/μg.
  • Validations

    Human Cathepsin S / CTSS Protein (His Tag) SDS-PAGE

    Human Cathepsin S / CTSS Protein (His Tag) SDS-PAGE

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"