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Product Name
Mouse Cathepsin S/CTSS (His Tag) recombinant protein
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Description
Thiol protease. Key protease responsible for the removal of the invariant chain from MHC class II molecules. The bond-specificity of this proteinase is in part similar to the specificities of cathepsin L and cathepsin N.
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Protein name
Cathepsin S
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Protein short names
MGC3886; CATHEPSIN S; CTSS; CAT S
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Uniprot ID
O70370
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Gene Name
Ctss; Cats
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Source/Expression Host
Human Cells
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Expression Plasmid/cDNA
A DNA sequence encoding the full length of mouse CTSS (AAB94925.1) (Met 1-Ile 340) was expressed, with a C-terminal polyhistidine tag.
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Protein Species
Mouse
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Molecular weight
The recombinant mouse CTSS consists of 334 amino acids and predicts a molecular mass of 37.6 KDa. In SDS-PAGE under reducing conditions, the apparent molecular mass of rmCTSS is approximately 33-38 KDa.
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Purity
> 90 % as determined by SDS-PAGE
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Activity
Measured by its ability to cleave the fluorogenic peptide substrate, Mca-RPKPVENval-WRK (Dnp)-NH2, AnaSpec, Catalog # 27114.
The specific activity is >300 pmoles/min/μg. -
Validations
Mouse Cathepsin S / CTSS Protein (His Tag) SDS-PAGE
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