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Product Name
Human Carboxypeptidase M/CPM (His Tag) recombinant protein
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Description
Specifically removes C-terminal basic residues (Arg or Lys) from peptides and proteins. It is believed to play important roles in the control of peptide hormone and growth factor activity at the cell surface, and in the membrane-localized degradation of extracellular proteins.
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Protein name
Carboxypeptidase M
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Protein short names
1110060I01RIK; CPM; CARBOXYPEPTIDASE M; AA589379; MGC118152; E030045M14RIK; 5730456K23RIK
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Uniprot ID
P14384
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Gene Name
CPM
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Source/Expression Host
Human Cells
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Expression Plasmid/cDNA
A DNA sequence encoding the human CPM (NP_938079.1) without the propeptide (Met 1-His 422) was expressed, fused with a polyhistidine tag at the C-terminus.
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Protein Species
Human
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Molecular weight
The secreted recombinant human CPM comprises 416 amino acids and has a predicted molecular mass of 47.7 kDa as estimated in SDS-PAGE under reducing conditions.
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Purity
> 98 % as determined by SDS-PAGE
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Activity
Measured by its ability to release Larginine from BenzoylAlaArg, with detection of the arginine amino group by ophthaldialdehyde.
The specific activity is >40,000 pmoles/min/μg. -
Validations
Human Carboxypeptidase M / CPM Protein (His Tag) SDS-PAGE
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