Rabbit Polyclonal to Human CPM
Human Carboxypeptidase M / CPM
1110060I01Rik antibody; 5730456K23Rik antibody; AA589379 antibody; Carboxypeptidase M antibody; Carboxypeptidase M antibody; Cpm antibody; CPM antibody; E030045M14Rik antibody; MGC118152 antibody; AA589379 antibody; 1110060I01Rik antibody; 5730456K23Rik antibody; E030045M14Rik antibody
Produced in rabbits immunized with purified, recombinant Human Carboxypeptidase M / CPM . Carboxypeptidase M / CPM specific IgG was purified by Human Carboxypeptidase M / CPM affinity chromatography.
0.2 μm filtered solution in PBS
This antibody can be stored at 2℃-8℃ for one month without detectable loss of activity. Antibody products are stable for twelve months from date of receipt when stored at -20℃ to -80℃. Preservative-Free.
Sodium azide is recommended to avoid contamination (final concentration 0.05%-0.1%). It is toxic to cells and should be disposed of properly. Avoid repeated freeze-thaw cycles.
ELISA: 0.1-0.2 μg/ml
This antibody can be used at 0.1-0.2 with the appropriate secondary reagents to detect Human Carboxypeptidase M / CPM.
IHC-P: 0.05-1 μg/mL
Human Carboxypeptidase M/CPM Immunohistochemistry(IHC) 14869
Carboxypeptidase M, also known as CPM, is a membrane-bound arginine/lysine carboxypeptidase which is a member of the carboxypeptidases family. These enzymes remove C-terminal amino acids from peptides and proteins and exert roles in the physiological processes of blood coagulation/fibrinolysis, inflammation, food digestion and pro-hormone and neuropeptide processing. Among the carboxypeptidases CPM is of particular importance because of its constitutive expression in an active form at the surface of specialized cells and tissues in the human body. CPM in the brain appears to be membrane-bound via a phosphatidylinositol glycan anchor. CPM is widely distributed in a variety of tissues and cells. The amino acid sequence of CPM indicated that the C-terminal hydrophobic region might be a signal for membrane attachment via a glycosylphosphatidylinositol (GPI) anchor. CPM is involved in peptide metabolism on both the cell surface and in extracellular fluids. CPM functions not only as a protease but also as a binding partner in cell-surface protein-protein interactions.
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