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Product Name
Calretinin antibody
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Description
Calretinin Rabbit Polyclonal antibody. Positive WB detected in fetal human brain tissue, human brain tissue, human colon tissue, human ileum tissue, mouse colon tissue, rat brain tissue. Positive IHC detected in human brain tissue, human appendix tissue, human cerebellum tissue, human colon cancer tissue, human ovary tumor tissue, human testis tissue. Observed molecular weight by Western-blot: 29 kDa
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Tested applications
ELISA, WB, IHC
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Species reactivity
Human,Mouse,Rat; other species not tested.
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Alternative names
29 kDa calbindin antibody; CAB29 antibody; CAL2 antibody; CALB2 antibody; calbindin 2 antibody; Calretinin antibody
- Immunogen
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Isotype
Rabbit IgG
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Preparation
This antibody was obtained by immunization of Calretinin recombinant protein (Accession Number: NM_001740). Purification method: Antigen affinity purified.
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Clonality
Polyclonal
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Formulation
PBS with 0.1% sodium azide and 50% glycerol pH 7.3.
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Storage instructions
Store at -20℃. DO NOT ALIQUOT
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Applications
Recommended Dilution:
WB: 1:1000-1:10000
IHC: 1:50-1:500
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Validations
Immunohistochemistry of paraffin-embedded human brain tissue slide using Catalog No:108909(Calretinin Antibody) at dilution of 1:200 (under 10x lens).
Immunohistochemistry of paraffin-embedded human brain tissue slide using Catalog No:108909(Calretinin Antibody) at dilution of 1:200 (under 40x lens).
fetal human brain tissue were subjected to SDS PAGE followed by western blot with Catalog No:108909(Calretinin Antibody) at dilution of 1:2000
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Background
Calbindin 2 (calretinin), is an intracellular calcium-binding protein belonging to the troponin C superfamily. Members of this protein family have six EF-hand domains which bind calcium. This protein plays a role in diverse cellular functions, including message targeting and intracellular calcium buffering. It also functions as a modulator of neuronal excitability, and is a diagnostic marker for some human diseases, including Hirschsprung disease and some cancers. Calretinin is a useful marker for differentiating malignant mesothelioma from carcinomas.
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