-
Product Name
Human CLEC10A/MGL1/CD301 (Fc Tag) recombinant protein
- Documents
-
Description
Probable role in regulating adaptive and innate immune responses. Binds in a calcium-dependent manner to terminal galactose and N-acetylgalactosamine units, linked to serine or threonine. These sugar moieties are known as Tn-Ag and are expressed in a variety of carcinoma cells.
-
Protein name
C-type lectin domain family 10 member A
-
Protein short names
MGL1; CD301A; HML2; M-ASGP-BP-1; CLEC10A; CD301; CLECSF14; CLECSF13; DN-160I24.1; MGL; HML
-
Uniprot ID
Q8IUN9
-
Gene Name
CLEC10A; CLECSF13; CLECSF14; HML
-
Source/Expression Host
Human Cells
-
Expression Plasmid/cDNA
A DNA sequence encoding the human CLEC10A (Q8IUN9-2) (Gln61-His292) was expressed, with the fused Fc region of human IgG1 at the N-terminus.
-
Protein Species
Human
-
Molecular weight
The recombinant human CLEC10A/Fc is a disulfide-linked homodimer. The reduced monomer comprises 492 amino acids and has a predicted molecular mass of 54.6 kDa. The apparent molecular mass of the protein is approximately 58 kDa in SDS-PAGE under reducing conditions due to glycosylation.
-
Purity
> 85 % as determined by SDS-PAGE
-
Validations
Human CLEC10A / MGL1 / CD301 Protein (Fc Tag) SDS-PAGE
Related Products / Services
Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"