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Product Name
Human CCL3/Mip1a (His Tag) recombinant protein
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Description
CCL3 is a cytokine belonging to the CC chemokine family. Chemokines are a family of structurally related leukocyte chemoattractant cytokines that play a central role during immunoregulatory and inflammation processes. All chemokines contain four conserved cysteines linked by disulfide bonds, and two major subfamilies, namely CXC and CC, are defined on the basis of the first two cysteines which are separated by one amino acid or are adjacent. CCL3 is involved in the acute inflammatory state in the recruitment and activation of polymorphonuclear leukocytes.
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Protein name
C-C motif chemokine
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Protein short names
SCYA3; C-C MOTIF CHEMOKINE 3; HEPARIN-BINDING CHEMOTAXIS PROTEIN; SMALL INDUCIBLE CYTOKINE A3 (HOMOLOGOUS TO MOUSE MIP-1A); L2G25B; MIP1 (A); MIP1-(A); SMALL INDUCIBLE CYTOKINE A3; RP23-320E6.7; MIP-1ALPHA; G0S19-1; MIP-1 ALPHA; TY-5; AI323804; MACROPHAGE INFLAMMATORY PROTEIN-1ALPHA; MIP-1-ALPHA; G0/G1 SWITCH REGULATORY PROTEIN 19-1; MIP1A; LD78ALPHA; MIP1-ALPHA; SIS-BETA; SIS-ALPHA; MACROPHAGE INFLAMMATORY PROTEIN 1-ALPHA; PAT 464.1; TONSILLAR LYMPHOCYTE LD78 ALPHA PROTEIN
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Uniprot ID
P10147
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Gene Name
CCL3; hCG_1749202
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Source/Expression Host
Yeast
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Expression Plasmid/cDNA
A DNA sequence encoding human CCL3 (NP_002974.1) (Ala23-Ala92) was expressed with a polyhistidine tag at the C-terminus.
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Protein Species
Human
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Molecular weight
The recombinant human CCL3 consists of 80 amino acids and predicts a molecular mass of 9.2 KDa. It migrates as an approximately 14 KDa band in SDS-PAGE under reducing conditions.
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Purity
> 95 % as determined by SDS-PAGE
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Validations
Human CCL3 / Mip1a Protein (His Tag) SDS-PAGE
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