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BSAP,PAX5 antibody

Cat.#: 108601

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Special Price 239.0 USD

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Product Information

  • Product Name
    BSAP,PAX5 antibody
  • Documents
  • Description
    BSAP,PAX5 Rabbit Polyclonal antibody. Positive WB detected in Daudi cells, mouse spleen tissue. Positive IHC detected in human tonsillitis tissue. Observed molecular weight by Western-blot: 42 kDa
  • Tested applications
    ELISA, WB, IHC
  • Species reactivity
    Human, Mouse; other species not tested.
  • Alternative names
    BSAP antibody; paired box 5 antibody; Paired box protein Pax 5 antibody; PAX5 antibody
  • Isotype
    Rabbit IgG
  • Preparation
    This antibody was obtained by immunization of BSAP,PAX5 recombinant protein (Accession Number: NM_016734). Purification method: Antigen affinity purified.
  • Clonality
    Polyclonal
  • Formulation
    PBS with 0.02% sodium azide and 50% glycerol pH 7.3.
  • Storage instructions
    Store at -20℃. DO NOT ALIQUOT
  • Applications

    Recommended Dilution:

    WB: 1:200-1:2000

    IHC: 1:50-1:500

  • Validations

    Daudi cells were subjected to SDS PAGE followed by western blot with Catalog No:117248(BSAP,PAX5 Antibody) at dilution of 1:600

    Daudi cells were subjected to SDS PAGE followed by western blot with Catalog No:117248(BSAP,PAX5 Antibody) at dilution of 1:600

    Immunohistochemistry of paraffin-embedded human tonsillitis tissue slide using Catalog No:117248(BSAP,PAX5 Antibody) at dilution of 1:100 (under 10x lens). heat mediated antigen retrieved with Sodium Citrate buffer (pH6).

    Immunohistochemistry of paraffin-embedded human tonsillitis tissue slide using Catalog No:117248(BSAP,PAX5 Antibody) at dilution of 1:100 (under 10x lens). heat mediated antigen retrieved with Sodium Citrate buffer (pH6).

    Immunohistochemistry of paraffin-embedded human tonsillitis tissue slide using Catalog No:117248(BSAP,PAX5 Antibody) at dilution of 1:100 (under 40x lens). heat mediated antigen retrieved with Sodium Citrate buffer (pH6).

    Immunohistochemistry of paraffin-embedded human tonsillitis tissue slide using Catalog No:117248(BSAP,PAX5 Antibody) at dilution of 1:100 (under 40x lens). heat mediated antigen retrieved with Sodium Citrate buffer (pH6).

  • Background
    PAX5, also named B-cell specific activator protein (BSAP), is a member of the highly conserved paired box (PAX)-domain family of transcription factors. PAX5 is essential in normal B-cell lymphopoiesis. It is expressed in pro-B, pre-B and mature B lymphocytes but not in plasma cells. PAX5 is a common target in leukemogenesis of B-ALL ( B-lineage acute lymphoblastic leukemia) along with CDKN2A. Owing to its frequent deletion in B-ALL, PAX5 could be used as one of the molecular markers in diagnosis and monitoring of the disease. This antibody is specific to PAX5. It will not cross react with other PAX members.

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"