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Product Name
BMP4 antibody
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Description
BMP4 Rabbit Polyclonal antibody. Positive WB detected in mouse heart tissue, COLO 320 cells, human skeletal muscle tissue, rat heart tissue. Positive IHC detected in human lung tissue, human prostate hyperplasia tissue. Observed molecular weight by Western-blot: 50 kDa
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Tested applications
ELISA, IHC, WB
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Species reactivity
Human,Mouse,Rat; other species not tested.
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Alternative names
BMP 2B antibody; BMP 4 antibody; BMP2B antibody; BMP2B1 antibody; BMP4 antibody; Bone morphogenetic protein 2B antibody; bone morphogenetic protein 4 antibody; DVR4 antibody; MCOPS6 antibody; ZYME antibody
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Isotype
Rabbit IgG
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Preparation
This antibody was obtained by immunization of BMP4 recombinant protein (Accession Number: NM_001347914). Purification method: Antigen affinity purified.
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Clonality
Polyclonal
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Formulation
PBS with 0.1% sodium azide and 50% glycerol pH 7.3.
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Storage instructions
Store at -20℃. DO NOT ALIQUOT
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Applications
Recommended Dilution:
WB: 1:200-1:1000
IHC: 1:20-1:200
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Validations
Immunohistochemical of paraffin-embedded human lung using Catalog No:117198(BMP4 antibody) at dilution of 1:50 (under 10x lens)
Immunohistochemical of paraffin-embedded human lung using Catalog No:117198(BMP4 antibody) at dilution of 1:50 (under 40x lens)
mouse heart tissue were subjected to SDS PAGE followed by western blot with Catalog No:117198(BMP4 Antibody) at dilution of 1:300
rat heart tissue were subjected to SDS PAGE followed by western blot with Catalog No:117198(BMP4 Antibody) at dilution of 1:600
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Background
BMP4, also named as BMP2B and DVR4, belongs to the TGF-beta family. BMPs have been shown to promote astroglial differentiation both in vitro and in vivo. BMP4 have been shown to be components of serum and are thought to be responsible for this differentiation. are expressed mainly in neurons, with minimal expression detected in astrocytes and oligodendrocytes.
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References
- Chen LP, Li ZF, Ping M. Regulation of Olig2 during astroglial differentiation in the subventricular zone of a cuprizone-induced demyelination mouse model. Neuroscience. 221:96-107. 2012.
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