Product Name

BCS1L antibody

Documents

Description

BCS1L Mouse Monoclonal antibody. Positive IF detected in MCF-7. Positive IHC detected in human gliomas. Positive WB detected in Colo320 cells. Observed molecular weight by Western-blot: 47KD

Tested applications

ELISA, WB, IHC, IF

Species reactivity

human, mouse; other species not tested.

Alternative names

BCS1L antibody; h BCS1 antibody; h BCS antibody; GRACILE antibody; FLNMS antibody

Isotype

Mouse IgG1

Preparation

This antibody was obtained by immunization of BCS1L recombinant protein (Accession Number: NM_001320717). Purification method: Protein G purified.

Clonality

Monoclonal

Formulation

PBS with 0.02% sodium azide and 50% glycerol pH 7.3.

Storage instructions

Store at -20℃. DO NOT ALIQUOT

Applications

Recommended Dilution:

WB: 1:500-1:5000

IHC: 1:20-1:200

IF: 1:20-1:200

Validations

COLO 320 cells were subjected to SDS PAGE followed by western blot with Catalog No:107083(BCS1L antibody) at dilution of 1:1000

Immunohistochemical of paraffin-embedded human gliomas using Catalog No:107083(BCS1L antibody) at dilution of 1:50 (under 10x lens)

Immunohistochemical of paraffin-embedded human gliomas using Catalog No:107083(BCS1L antibody) at dilution of 1:50 (under 40x lens)

Immunofluorescent analysis of MCF-7 cells, using BCS1L antibody Catalog No: at 1:50 dilution and Rhodamine-labeled goat anti-mouse IgG (red).

Background

Human BCS1-like (BCS1L), a mitochondrial inner-membrane protein, is a chaperone necessary for the assembly of mitochondrial respiratory chain complex III. Recently studies indicated that the mutations in this protein may cause the GRACILE (growth retardation, aminoaciduria, cholestasis, iron overload, lactacidosis, and early death) syndrome, a recessively inherited lethal disease characterized by fetal growth retardation, lactic acidosis, aminoaciduria, cholestasis, and abnormalities in iron metabolism.

BCS1L antibody

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