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Product Name
BCAS2 Polyclonal Antibody
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Description
Polyclonal antibody to BCAS2
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Tested applications
WB, IHC, IF
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Species reactivity
Human, Mouse, Rat
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Alternative names
BCAS2 antibody; DAM1 antibody; SPF27 antibody; Snt309 antibody; pre-mRNA-splicing factor SPF27 antibody
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Isotype
Rabbit IgG
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Preparation
Antigen: Recombinant fusion protein containing a sequence corresponding to amino acids 1-225 of human BCAS2 (NP_005863.1).
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Clonality
Polyclonal
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Formulation
PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
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Storage instructions
Store at -20℃. Avoid freeze / thaw cycles.
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Applications
WB 1:500 - 1:2000
IHC 1:50 - 1:200
IF 1:50 - 1:200 -
Validations
Western blot - BCAS2 Polyclonal Antibody
Western blot analysis of extracts of various cell lines, using BCAS2 antibody at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) at 1:10000 dilution.Lysates/proteins: 25ug per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit .Exposure time: 90s.
Immunohistochemistry - BCAS2 Polyclonal Antibody
Immunohistochemistry of paraffin-embedded human lung cancer using BCAS2 antibody at dilution of 1:100 (40x lens).
Immunohistochemistry - BCAS2 Polyclonal Antibody
Immunohistochemistry of paraffin-embedded human esophagus using BCAS2 antibody at dilution of 1:100 (40x lens).
Immunohistochemistry - BCAS2 Polyclonal Antibody
Immunohistochemistry of paraffin-embedded mouse brain using BCAS2 antibody at dilution of 1:100 (40x lens).
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Background
Component of the PRP19-CDC5L complex that forms an integral part of the spliceosome and is required for activating pre-mRNA splicing. May have a scaffolding role in the spliceosome assembly as it contacts all other components of the core complex. The PRP19-CDC5L complex may also play a role in the response to DNA damage (DDR).
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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"