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BACH1 antibody

Cat.#: 108403

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Special Price 239.0 USD

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Product Information

  • Product Name
    BACH1 antibody
  • Documents
  • Description
    BACH1 Rabbit Polyclonal antibody. Positive IHC detected in human cervical cancer tissue. Positive WB detected in HEK-293 cells, HeLa cells, MCF7 cells. Observed molecular weight by Western-blot: 92 kDa
  • Tested applications
    ELISA, IHC, WB
  • Species reactivity
    Human,Mouse,Rat; other species not tested.
  • Alternative names
    BACH 1 antibody; BACH1 antibody; BTB and CNC homolog 1 antibody; HA2303 antibody
  • Immunogen
    Human BACH1 Recombinant protein (GST tag)
  • Isotype
    Rabbit IgG
  • Preparation
    This antibody was obtained by immunization of BACH1 recombinant protein (Accession Number: NM_001186). Purification method: Antigen affinity purified.
  • Clonality
    Polyclonal
  • Formulation
    PBS with 0.02% sodium azide and 50% glycerol pH 7.3.
  • Storage instructions
    Store at -20℃. DO NOT ALIQUOT
  • Applications

    Recommended Dilution:

    WB: 1:500-1:5000

    IHC: 1:20-1:200

  • Validations

    HEK-293 cells were subjected to SDS PAGE followed by western blot with Catalog No:108403(BACH1 antibody) at dilution of 1:1000

    HEK-293 cells were subjected to SDS PAGE followed by western blot with Catalog No:108403(BACH1 antibody) at dilution of 1:1000

    Immunohistochemical of paraffin-embedded human cervical cancer using Catalog No:108403(BACH1 antibody) at dilution of 1:100 (under 10x lens)

    Immunohistochemical of paraffin-embedded human cervical cancer using Catalog No:108403(BACH1 antibody) at dilution of 1:100 (under 10x lens)

    Immunohistochemical of paraffin-embedded human cervical cancer using Catalog No:108403(BACH1 antibody) at dilution of 1:100 (under 40x lens)

    Immunohistochemical of paraffin-embedded human cervical cancer using Catalog No:108403(BACH1 antibody) at dilution of 1:100 (under 40x lens)

  • Background
    BTB and CNC homology 1, basic leucine zipper transcription factor 1(BACH1) is a heme-regulated transcriptional regulator that acts as repressor or activator and a member of the AP-a superfamily. MafK belongs to the small Maf family that can funciton as transcriptional activators or repressors depending on the proteins with which they form heterdimers. BACH1 has crucial roles in both stress responses and transformation by H-RasV12
  • References
    • Kwok SC. Zinc Protoporphyrin Upregulates Heme Oxygenase-1 in PC-3 Cells via the Stress Response Pathway. International journal of cell biology. 2013:162094. 2013.

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"