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Product Name
ATXN10 antibody
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Description
ATXN10 Rabbit Polyclonal antibody. Positive WB detected in human brain tissue, HEK-293 cells, HeLa cells, human cerebellum tissue, human kidney tissue. Positive IHC detected in human ovary tumor tissue. Positive IF detected in Hela cells. Observed molecular weight by Western-blot: 50kd
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Tested applications
ELISA, WB, IHC, IF
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Species reactivity
Human,Mouse,Rat; other species not tested.
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Alternative names
ataxin 10 antibody; ATXN10 antibody; Brain protein E46 homolog antibody; E46L antibody; FLJ37990 antibody; SCA10 antibody
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Isotype
Rabbit IgG
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Preparation
This antibody was obtained by immunization of ATXN10 recombinant protein (Accession Number: NM_013236). Purification method: Antigen affinity purified.
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Clonality
Polyclonal
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Formulation
PBS with 0.02% sodium azide and 50% glycerol pH 7.3.
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Storage instructions
Store at -20℃. DO NOT ALIQUOT
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Applications
Recommended Dilution:
WB: 1:500-1:5000
IHC: 1:20-1:200
IF: 1:10-1:100
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Validations
human brain tissue were subjected to SDS PAGE followed by western blot with Catalog No:117068(ATXN10 antibody) at dilution of 1:500
Immunohistochemical of paraffin-embedded human ovary tumor using Catalog No:117068(ATXN10 antibody) at dilution of 1:100 (under 10x lens)
Immunohistochemical of paraffin-embedded human ovary tumor using Catalog No:117068(ATXN10 antibody) at dilution of 1:100 (under 40x lens)
Immunofluorescent analysis of Hela cells, using ATXN10 antibody Catalog No:117068 at 1:25 dilution and Rhodamine-labeled goat anti-rabbit IgG (red).
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Background
ATXN10, also named as SCA10, is a 475 amino acid protein, which belongs to the ataxin-10 family. ATXN10 is expressed in the central nervous system.ATXN10 is necessary for the survival of cerebellar neurons. ATXN10 may play a role in the maintenance of a critical intracellular glycosylation level and homeostasis.
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References
- Sang L, Miller JJ, Corbit KC. Mapping the NPHP-JBTS-MKS protein network reveals ciliopathy disease genes and pathways. Cell. 145(4):513-28. 2011.
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