ATXN1 Polyclonal Antibody

Cat.#: 164770

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Product Information

  • Product Name
    ATXN1 Polyclonal Antibody
  • Documents
  • Description
    Polyclonal antibody to ATXN1
  • Tested applications
    WB, IF
  • Species reactivity
    Human, Mouse, Rat
  • Alternative names
    ATXN1 antibody; ATX1 antibody; D6S504E antibody; SCA1 antibody; ataxin-1 antibody
  • Isotype
    Rabbit IgG
  • Preparation
    Antigen: Recombinant fusion protein containing a sequence corresponding to amino acids 586-815 of human ATXN1 (NP_001121636.1).
  • Clonality
    Polyclonal
  • Formulation
    PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
  • Storage instructions
    Store at -20℃. Avoid freeze / thaw cycles.
  • Applications
    WB 1:500 - 1:2000
    IF 1:10 - 1:100
  • Validations

    Western blot - ATXN1 Polyclonal Antibody

    Western blot - ATXN1 Polyclonal Antibody

    Western blot analysis of extracts of various cell lines, using ATXN1 antibody at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) at 1:10000 dilution.Lysates/proteins: 25ug per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit .Exposure time: 120s.

    Immunofluorescence - ATXN1 Polyclonal Antibody

    Immunofluorescence - ATXN1 Polyclonal Antibody

    Immunofluorescence analysis of HeLa cells using ATXN1 antibody .

  • Background
    Chromatin-binding factor that repress Notch signaling in the absence of Notch intracellular domain by acting as a CBF1 corepressor. Binds to the HEY promoter and might assist, along with NCOR2, RBPJ-mediated repression. Binds RNA in vitro. May be involved in RNA metabolism. In concert with CIC and ATXN1L, involved in brain development (By similarity).

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"