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Product Name
Anti-Ataxin 1 Rabbit antibody
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Description
Ataxin 1 Rabbit polyclonal antibody
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Tested applications
WB, IP
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Species reactivity
Human, Mouse, Rat
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Alternative names
ATX1; SCA1; D6S504E antibody
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Isotype
Rabbit IgG
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Preparation
Antigen: Recombinant protein of human Ataxin 1
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Clonality
Polyclonal
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Formulation
Supplied in 50nM Tris-Glycine(pH 7.4), 0.15M Nacl, 40%Glycerol, 0.01% sodium azide and 0.05% BSA.
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Storage instructions
Store at -20°C. Stable for 12 months from date of receipt.
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Applications
WB: 1/1000
IP: 1/20
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Validations
Western blot detection of Ataxin 1 in 3T3 cell lysates using Ataxin 1 Rabbit pAb(1:1000 diluted).Predicted band size:87kDa.Observed band size:105kDa.
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Background
Swiss-Prot Acc.P54253.Chromatin-binding factor that repress Notch signaling in the absence of Notch intracellular domain by acting as a CBF1 corepressor. Binds to the HEY promoter and might assist, along with NCOR2, RBPJ-mediated repression. Binds RNA in vitro. May be involved in RNA metabolism (PubMed:21475249). In concert with CIC and ATXN1L, involved in brain development .
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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"