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Product Name
ATN1 antibody
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Description
ATN1 Rabbit Polyclonal antibody. Positive IHC detected in human ovary tissue, human testis tissue. Positive WB detected in mouse testis tissue. Observed molecular weight by Western-blot: 105-110 kDa
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Tested applications
ELISA, WB, IHC
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Species reactivity
Human, Mouse; other species not tested.
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Alternative names
ATN1 antibody; atrophin 1 antibody; B37 antibody; D12S755E antibody; DRPLA antibody; HRS antibody; NOD antibody
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Isotype
Rabbit IgG
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Preparation
This antibody was obtained by immunization of ATN1 recombinant protein (Accession Number: NM_001940). Purification method: Antigen affinity purified.
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Clonality
Polyclonal
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Formulation
PBS with 0.1% sodium azide and 50% glycerol pH 7.3.
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Storage instructions
Store at -20℃. DO NOT ALIQUOT
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Applications
Recommended Dilution:
WB: 1:200-1:1000
IHC: 1:20-1:200
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Validations
mouse testis tissue were subjected to SDS PAGE followed by western blot with Catalog No:108334(ATN1 Antibody) at dilution of 1:300
Immunohistochemistry of paraffin-embedded human ovary tissue slide using Catalog No:108334(ATN1 Antibody) at dilution of 1:50 (under 10x lens)
Immunohistochemistry of paraffin-embedded human ovary tissue slide using Catalog No:108334(ATN1 Antibody) at dilution of 1:50 (under 40x lens)
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Background
ATN1 also known as Atrophin-1 is a protein that in humans is encoded by the ATN1 gene. Dentatorubral pallidoluysian atrophy is a rare neurodegenerative disorder characterized by cerebellar ataxia, myoclonic epilepsy, choreoathetosis, and dementia. The disorder is related to the expansion of a trinucleotide repeat within this gene. The encoded protein includes a serine repeat and a region of alternating acidic and basic amino acids, as well as the variable glutamine repeat.
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