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Product Name
ASTN2 antibody
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Description
ASTN2 Rabbit Polyclonal antibody. Positive IHC detected in human brain tissue. Positive WB detected in HepG2 cells. Observed molecular weight by Western-blot: 148 kDa
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Tested applications
ELISA, WB, IHC
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Species reactivity
Human,Mouse,Rat; other species not tested.
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Alternative names
ASTN2 antibody; astrotactin 2 antibody; bA67K19.1 antibody; KIAA0634 antibody
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Isotype
Rabbit IgG
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Preparation
This antibody was obtained by immunization of ASTN2 recombinant protein (Accession Number: NM_198186). Purification method: Antigen affinity purified.
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Clonality
Polyclonal
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Formulation
PBS with 0.1% sodium azide and 50% glycerol pH 7.3.
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Storage instructions
Store at -20℃. DO NOT ALIQUOT
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Applications
Recommended Dilution:
WB: 1:200-1:1000
IHC: 1:20-1:200
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Validations
HepG2 cells were subjected to SDS PAGE followed by western blot with Catalog No:108273(ASTN2 Antibody) at dilution of 1:300
Immunohistochemistry of paraffin-embedded human brain tissue slide using Catalog No:108273(ASTN2 Antibody) at dilution of 1:50 (under 10x lens)
Immunohistochemistry of paraffin-embedded human brain tissue slide using Catalog No:108273(ASTN2 Antibody) at dilution of 1:50 (under 40x lens)
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Background
ASTN2, also named as KIAA0634, has recently been implicated in several common disorders of the nervous system, including attention deficit hyperactivity disorder (ADHD), autism and schizophrenia. Astn2 is abundant in migrating cerebellar granule neurons when glial-guided migration is ongoing. ASTN2 forms a complex with ASTN1 that regulates the polarized trafficking of ASTN1 during migration.
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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"