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Product Name
Human ASGR2 / ASGPR2 (His Tag) recombinant protein
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Description
Mediates the endocytosis of plasma glycoproteins to which the terminal sialic acid residue on their complex carbohydrate moieties has been removed. The receptor recognizes terminal galactose and N-acetylgalactosamine units. After ligand binding to the receptor, the resulting complex is internalized and transported to a sorting organelle, where receptor and ligand are disassociated. The receptor then returns to the cell membrane surface.
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Protein name
Asialoglycoprotein receptor 2
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Protein short names
ASGR-2; ASGR; CLEC4H2; DN-490M13.1; ASGP-R2; HBXBP; HL-2; FLJ60040; ASGPR2
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Uniprot ID
P07307
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Gene Name
ASGR2; CLEC4H2
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Source/Expression Host
Human Cells
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Expression Plasmid/cDNA
A DNA sequence encoding the human ASGR2 (P07307-1) (Gln80-Ala311) was expressed, with an N-terminal polyhistidine tag.
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Protein Species
Human
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Molecular weight
The recombinant human ASGR2 comprises 252 amino acids and has a predicted molecular mass of 28.9 kDa. The apparent molecular mass of the protein is approximately 37-42 kDa in SDS-PAGE under reducing conditions due to glycosylation.
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Purity
> 95 % as determined by SDS-PAGE
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Validations
Human ASGR2 Protein (His Tag) SDS-PAGE
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