-
Product Name
Apolipoprotein H antibody
- Documents
-
Description
Apolipoprotein H Mouse Monoclonal antibody. Positive WB detected in Human testis. Positive IHC detected in human liver tissue. Observed molecular weight by Western-blot: 50kd
-
Tested applications
ELISA, WB, IHC
-
Species reactivity
Human; other species not tested.
-
Alternative names
Anticardiolipin cofactor antibody; APC inhibitor antibody; Apo H antibody; APOH antibody; Apolipoprotein H antibody; B2G1 antibody; B2GPI antibody; Beta 2 glycoprotein 1 antibody; Beta 2 glycoprotein I antibody; Beta(2)GPI antibody
-
Isotype
Mouse IgG1
-
Preparation
This antibody was obtained by immunization of Apolipoprotein H recombinant protein (Accession Number: NM_000042). Purification method: Protein G purified.
-
Clonality
Monoclonal
-
Formulation
PBS with 0.02% sodium azide and 50% glycerol pH 7.3.
-
Storage instructions
Store at -20℃. DO NOT ALIQUOT
-
Applications
Recommended Dilution:
WB: 1:500-1:5000
IHC: 1:20-1:200
-
Validations
human testis tissue were subjected to SDS PAGE followed by western blot with Catalog No:107066(APOH antibody) at dilution of 1:1000
Immunohistochemical of paraffin-embedded human liver using Catalog No:107066(APOH antibody) at dilution of 1:50 (under 10x lens)
Immunohistochemical of paraffin-embedded human liver using Catalog No:107066(APOH antibody) at dilution of 1:50 (under 40x lens)
-
Background
Apolipoprotein H (ApoH), also known as beta2-glycoprotein I (B2-GPI), is a plasma glycoprotein, primarily synthesized in the liver. It has an important function in blood coagulation and clearance of apoptotic bodies from the circulation. ApoH is also an important actor of host innate immune response through its capacity to bind with high affinity to a large panel of pathogens or their proteins.
-
References
- Tang L, Zeng W, Lu X. Identification of APOH polymorphisms as common genetic risk factors for venous thrombosis in the Chinese population. Journal of thrombosis and haemostasis : JTH. 12(10):1616-25. 2014.
Related Products / Services
Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"