Mouse ApoA1 (Fc Tag) recombinant protein

Cat.#: 501678

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Product Information

  • Product Name
    Mouse ApoA1 (Fc Tag) recombinant protein
  • Documents
  • Description
    Participates in the reverse transport of cholesterol from tissues to the liver for excretion by promoting cholesterol efflux from tissues and by acting as a cofactor for the lecithin cholesterol acyltransferase (LCAT). As part of the SPAP complex, activates spermatozoa motility.
  • Protein name
    Apolipoprotein A-I
  • Protein short names
    APO-AI; BRP-14; ALP-1; MGC102525; LTW-1; APOA-I; MGC117399; APOA-1; 42249; 42248; LVTW-1
  • Uniprot ID
    Q00623
  • Gene Name
    Apoa1
  • Source/Expression Host
    Human Cells
  • Expression Plasmid/cDNA
    A DNA sequence encoding the mouse APOA1 (Q00623) (Met 1-Gln 264) was fused with the Fc region of human IgG1 at the C-terminus.
  • Protein Species
    Mouse
  • Molecular weight
    The secreted recombinant mouse APOA1/Fc is a disulfide-linked homodimer. The reduced monomer comprises 487 amino acids and has a calculated molecular mass of 55.8 kDa. As a result of glycosylation, the apparent molecular mass of rmAPOA1/Fc monomer is approximately 60 kDa in SDS-PAGE under reducing conditions.
  • Purity
    > 90 % as determined by SDS-PAGE
  • Activity
    1. Measured by its binding ability in a functional ELISA.
    2. Immobilized mouse ApoAI at 10 μg/mL (100 μl/well) can bind  biotinylated human SCARB1, The EC50 of biotinylated human SCARB1 is 0.27 μg/mL.
  • Validations

    Mouse APOA1 Protein (Fc Tag) SDS-PAGE

    Mouse APOA1 Protein (Fc Tag) SDS-PAGE

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"